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Task 03: Configure Microsoft Defender Safe Attachments

Enable Safe Attachments to scan and detonate email and collaboration-file attachments in a secure sandbox, blocking malicious content before it reaches users.

  1. In the leftmost pane, select Email & collaboration > Policies & rules > Threat policies.

    05-MDO-Settings-1.png

  2. Select Safe Attachments.

    16-MDO-Settings-12.png

  3. Select Global settings.

    17-MDO-Settings-13.png

  4. Ensure the following options are enabled:

    • Defender for Office 365 for SharePoint, OneDrive, and Microsoft Teams
    • Safe Documents for Office clients

    18-MDO-Settings-14.png

  5. If necessary, select Save.

    19-MDO-Settings-15.png

    Confirm Safe Attachments is active. It detonates attachments at delivery time to detect and block malicious files across Exchange, SharePoint, OneDrive, and Teams.